Professor Kehinde Okonjo

Professor of Biophysical Chemistry

BSc; PhD

Contents

  1. College
  2. School
  3. Department
  4. Programme
  5. Research Interests
  6. Awards & Honours
  7. Teaching Areas
  8. Current Postgraduate Supervision
  9. Selected Publications (17)
  10. Summary of Profile
  11. Curriculum Vitae

College

College of Science and Technology

School

Departments

Department

Chemistry

Programme

Animal and Environmental Biology

Research Interests

Kinetics and equilibrium of the reaction of protein sulphydryl groups with Ellman's reagent, 5,5'-dithiobis(2-nitrobenzoate).

Awards & Honours

Federal Government of Nigeria Scholarship, 1964-1967 for first degree.

Studentship of the National Institutes of Health (U.S.A.), 1970 – 1972, from a grant awarded to my PhD supervisor, Professor John G. Beetlestone.

Fellowship of the Alexander von Humboldt Foundation, Bonn, Germany, for postdoctoral studies at the Max Planck Institute for Biophysical Chemistry, Goettingen, 1973 – 1975.

Fellowship of the Alexander von Humboldt Foundation, Bonn, Germany, for research at the Max Planck Institute for Physiological Chemistry, Dortmund, 1989-1990.

Fellowship of the Max Planck Society, Germany, for research at the Max Planck Institute for Physiological Chemistry, Dortmund, 1990 -1991.

Winner of the Royal Society of Chemistry Grant for International Authors (1998) in recognition of my publications in The Journal of the Chemical Society(Faraday Transactions), an international journal of physical chemistry.

Teaching Areas

Physical Chemistry and Physical Biochemistry courses at the undergraduate and postgraduate levels.

Current Postgraduate Supervision

Omolola E. Omotosho, Dept. of Biological Sciences: PhD
Abiola Edobor-Osor, Dept. of Chemistry: MSc

Selected Publications (17)

1. Desensitization is a property of the cholinergic binding region of the

[ Download 277.10 kB ]

2. REACTIVITIES OF THE SULPHYDRYL GROUPS OF DOG HEMOGLOBIN

[ Download 641.06 kB ]

3. A second pathway of activation of the Torpedo acetylcholine receptor channel

[ Download 705.55 kB ]

4. The Effect of Heme-linked Ionizable Groups on Cyanide Binding to Methemoglobin

[ Download 689.92 kB ]

5. Role of the Relaxation of the Iron(ll1) Ion Spin States Equilibrium in the Kinetics of Ligand Binding to Methaemoglobin

[ Download 598.40 kB ]

6. Ligand-dependent reactivity of the CysB5[23] b sulfhydryl group of the major haemoglobin of chicken

[ Download 272.14 kB ]

7. Tertiary conformational transition in sheep hemoglobins induced by reaction with 5,5´-dithiobis(2-nitrobenzoate) and by binding of inositol hexakisphosphate

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8. Subunit iron spin heterogeneity in human aquomethemoglobin A

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9. Reversible reaction of 5,5V-dithiobis(2-nitrobenzoate) with the hemoglobins of the domestic cat: Acetylation of NH3 terminal group of the h chain transforms the complex pH dependence of the forward apparent second order rate constant to a simple form

[ Download 219.13 kB ]

10. Reversible reaction of 5,5′-dithiobis(2-nitrobenzoate) with the CysF9[93]β sulfhydryl groups of the hemoglobins of the domestic cat: Variation of the equilibrium and reverse rate constants with pH

[ Download 186.86 kB ]

11. Transition of hemoglobin between two tertiary conformations: The transition constant differs significantly for the major and minor hemoglobins of the Japanese quail (Cortunix cortunix japonica)

[ Download 450.20 kB ]

12. Transition of hemoglobin between two tertiary conformations: Determination of equilibrium and thermodynamic parameters from the reaction of 5,5′-dithiobis(2-nitrobenzoate) with the CysF9[93]β sulfhydryl group

[ Download 510.96 kB ]

13. Transition of haemoglobin between two tertiary conformations: Inositol hexakisphosphate increases the transition constant and the affinity of sheep haemoglobin for 5,5′-dithiobis(2-nitrobenzoate)

[ Download 1.23 MB ]

14. The uptake of protons by heme-linked ionizable groups on azide binding to methemoglobin

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15. Effect of Organic Phosphates on the Sulfhydryl Reactivities of Oxyhemoglobins A and S*

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16. Relaxation amplitude analysis of thiocyanate and formate binding to human

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17. Temperature-jump Studies on Hemoglobin: Kinetic Evidence for a Non-quaternary Isomerization Process in

[ Download 705.55 kB ]

Summary of Profile

Born 1942. Educated King's College, Lagos (1957-63). BSc, PhD (University of Ibadan). Retired Professor of Chemistry, University of Ibadan. Currently Professor of Chemistry, Covenant University. Current research interests: Kinetics and thermodynamics of reactions of reaction of Ellman's reagent with hemoglobin sulphydryl groups. Publications in such high impact journals as the Journal of Biological Chemistry, the Journal of Molecular Biology, the Journal of the Chemical Society (Faraday Transactions), FEBS letters, Biochimica et Biophysica Acta, European Journal of Biochemistry, Biophysical Chemistry. Married 1974 to Chinwe Adigwe (nee Esimai). Five children, all girls, all well educated having studied medicine (2), law (1), economics and business (1) and geology (1) up to masters degree level.

Curriculum Vitae

Kehinde Okonjos CV.doc 118.00 kB
 
 
Last Updated:

12/06/2010 02:40 pm